MC-Val-Ala-PBD 是抗体偶联药物的一部分 (drug-linker conjugate for ADC)，它由 PBD (一种细胞毒性 DNA 交联剂) 和可切割的 MC-Val-Ala 连接而成。
货号:ajcx16566
CAS:1342820-51-2
分子式:C60H64N8O12
分子量：1089.2
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

MC-Val-Ala-PBD is a drug-linker conjugate for ADC by using the antitumor antibiotic, pyrrolobenzodiazepine (PBD, a cytotoxic DNA crosslinking), linked via the cleavable linker MC-Val-Ala[1].

[1]. Jeffrey SC, et al. A potent anti-CD70 antibody-drug conjugate combining a dimeric pyrrolobenzodiazepine drug with site-specific conjugation technology. Bioconjug Chem. 2013 Jul 17;24(7):1256-63.