CBS1117

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CBS1117

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

规格:	98%
分子量:	315.24

包装与价格：

包装	价格(元)
5mg	询价
10mg	询价
25mg	询价
50mg	询价
100mg	询价

CBS1117 抑制病毒进入，对甲型流感病毒 A/Puerto Rico/8/34 (H1N1) 的 IC50 为 70 nM。CBS1117 干扰血凝素 (HA) 介导的融合过程。
货号:ajcx33084
CAS:959245-08-0
分子式:C15H20Cl2N2O
分子量：315.24
溶解度:DMSO : 250 mg/mL (793.05 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

CBS1117 is a virus entry inhibitor with an IC50 of 70 nM for influenza A virus, A/Puerto Rico/8/34 (H1N1). CBS1117 interferes with the hemagglutinin (HA)-mediated fusion process[1].

CBS1117 has a lower IC50 value of 70 nM and higher CC50 value of 274 μM, leading to an excellent antiviral selectivity index value (SI value of 3914) in human lung epithelial cell line (A549)[1].

[1]. Hussein AFA, et al. Identification of entry inhibitors with 4-aminopiperidine scaffold targeting group 1 influenza A virus. Antiviral Res. 2020 May;177:104782.