MC-Val-Cit-PAB-MMAF是一种偶联药物(drug-linkerconjugateforADC)，具有抗肿瘤活性，由抗微管蛋白抑制剂MMAF和组织蛋白酶可降解(cleavable)的linkerMC-Val-Cit-PAB连接而成。
货号:ajcx31008
CAS:863971-17-9
分子式:C68H103N11O16
分子量：1330.61
溶解度:DMSO: 100 mg/mL (75.15 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

MC-Val-Cit-PAB-MMAF is a drug-linker conjugate for ADC with antitumor activity by using the tubulin inhibitor, MMAF, linked via cathepsin cleavable MC-Val-Cit-PAB.

[1]. Cheng X, et al. MORAb-202, an Antibody-Drug Conjugate Utilizing Humanized Anti-human FRα Farletuzumab and the Microtubule-targeting Agent Eribulin, has Potent Antitumor Activity. Mol Cancer Ther. 2018 Dec;17(12):2665-2675.