A fungal metabolite
货号:ajcx24774
CAS:105364-56-5
分子式:C13H12O5
分子量：248.2
溶解度:
纯度：98%
存储：Store at -20°C
库存：
现货Background:
WF-3681 is a butenolide fungal metabolite that has been found inAcremonium.1It inhibits aldose reductase (IC50= 0.25 µM for the rabbit lens enzyme).2
1.Ghisalberti, E.L., Hargreaves, J.R., and McConville, E.Butenolides from a cultured microfungus, Acremonium spNat. Prod. Res.18(2)105-109(2004)
2.Nishikawa, M., Yoshida, K., Okamoto, M., et al.Studies on WE-3681, a novel aldose reductase inhibitor. III. Effects of WF-3681 and its derivatives on sorbitol accumulation in diabetic ratsJ. Antibiot. (Tokyo)43(9)1186-1188(1990)
