A dopamine D1 and D5 receptor partial agonist
货号:ajcx24336
CAS:1643489-24-0
分子式:C19H16F3N3O3
分子量：391.3
溶解度:DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:20): 0.05 mg/ml,Ethanol: 2 mg/ml
纯度：98%
存储：Store at -20°C
库存：
现货Background:
PF-06649751 is a dopamine D1and D5receptor partial agonist.1It increases locomotor activity and reduces a global parkinsonian disability score in a macaque model of Parkinson's disease induced by MPTP when administered at a dose of 0.04 mg/kg.
1.Young, D., Popiolek, M., Trapa, P., et al.D1 agonist improved movement of parkinsonian nonhuman primates with limited dyskinesia side effectsACS Chem. Neurosci.11(4)560-566(2020)
