A mixture that acts as an AhR agonist
货号:ajcx21048
CAS:N/A
分子式:C18H9ClN2O
分子量:304.7
溶解度:DMSO: soluble
纯度:98%
存储:Store at -20°C
库存:
现货Background:
10(11)-Cl-BBQ mixture contains the 10-Cl-BBQ and 11-Cl-BBQ congeners of Cl-BBQ and acts as an aryl hydrocarbon receptor (AhR) agonist.1It induces transcription of the AhR target cytochrome P450 (CYP) isoformCyp1a1in mouse liver when administered intraperitoneally at a dose of 10 mg/kg. This product is a mixture of 10-Cl-BBQ and 11-Cl-BBQ.
1.Ehrlich, A.K., Pennington, J.M., Bisson, W.H., et al.TCDD, FICZ, and other high affinity AhR ligands dose-dependently determine the fate of CD4+ T cell differentiationToxicol. Sci.161(2)310-320(2018)