Asperfuran 是一种由米曲霉菌株生产的抗真菌二氢苯并呋喃衍生物。
货号:ajcx20524
CAS:129277-10-7
分子式:C13H14O3
分子量：218.3
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Asperfuran is a fungal metabolite originally isolated from A. oryzae that has antifungal and anticancer activities.1 It inhibits the growth of 23 fungi in a disc assay when used at a concentration of 50 μg per disc. Asperfuran inhibits chitin synthase with an IC50 value of 300 μM. It inhibits proliferation of HeLa S3 and L1210 cancer cells (IC50s = 25 μg/ml for both).

|1. Pfefferle, W., Anke, H., Bross, M., et al. Asperfuran, a novel antifungal metabolite from Aspergillus oryzae. J. Antibiot. (Tokyo) 43(6), 648-654 (1990).