E3 ligase Ligand-Linker Conjugates 48 包含用于 E3 泛素连接酶的 MDM2 配体和 linker。E3 ligase Ligand-Linker Conjugates 48 可通过 PROTAC 技术合成降解剂。
货号:ajcx13882
CAS:N/A
分子式:C42H52Cl2N8O9
分子量：883.82
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

E3 ligase Ligand-Linker Conjugates 48 incorporates a MDM2 ligand for the E3 ubiquitin ligase, and a PROTAC linker. E3 ligase Ligand-Linker Conjugates 48 can be used to design PROTAC degrader[1]. MDM2

[1]. Gu S, et al. PROTACs: An Emerging Targeting Technique for Protein Degradation in Drug Discovery. Bioessays. 2018 Apr;40(4):e1700247.