Fresolimumab (GC1008) 是一种高亲和力的全人单克隆抗体,可中和人 TGFβ1、TGFβ2 和 TGFβ3 的活性形式。Fresolimumab 可用于癌症和纤维性疾病的研究。
货号:ajcx39778
CAS:948564-73-6
分子式:N/A
分子量:N/A
溶解度:N/A
纯度:98%
存储:Store at -20°C
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现货Background:
Fresolimumab (GC1008) is a high-affinity fully human monoclonal antibody that neutralizes the active form of human TGFβ1, TGFβ2, and TGFβ3. Fresolimumab can be used for the research of cancer and fibrotic diseases [1].
[1]. Morris JC, et al. Phase I study of GC1008 (fresolimumab): a human anti-transforming growth factor-beta (TGFβ) monoclonal antibody in patients with advanced malignant melanoma or renal cell carcinoma. PLoS One. 2014;9(3):e90353. Published 2014 Mar 11.