O-Noruciferine 是荷叶的一种卟啉型生物碱，是一种有效的 hERG 通道抑制剂。
货号:ajcx35072
CAS:3153-55-7
分子式:C18H19NO2
分子量：281.35
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

O-Nornuciferine, an aporphine-type alkaloid from lotus leaf, is a potent hERG channel inhibitor[1].

O-Nornuciferine has an IC50 of 7.91 μM in vitro hERG blockages measured in HEK293 cells[1]. O-Nornuciferine (100 μM) has 47% hERG channel inhibition in Xenopus oocytes by lotus alkaloids[1].

[1]. Ulrike Grienke, et al. Human Ether-À-go-go Related Gene (hERG) Channel Blocking Aporphine Alkaloids From Lotus Leaves and Their Quantitative Analysis in Dietary Weight Loss Supplements. J Agric Food Chem. 2015 Jun 17;63(23):5634-9.