(R)-M8891 (compound R-9) 是 M8891 低活性的异构体。M8891 是一种具有口服活性,可逆的且能透过血脑屏障的甲硫氨酸氨基肽酶 2 (MetAP-2) 抑制剂。
货号:ajcx34322
CAS:2575547-29-2
分子式:C20H17F2N3O3
分子量:385.36
溶解度:DMSO : 140 mg/mL (363.30 mM; Need ultrasonic)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
(R)-M8891 (compound R-9) is a less active isomer of M8891. M8891 is an orally active, reversible and brain penetrant Methionine Aminopeptidase-2 (MetAP-2) inhibitor[1].
[1]. Timo Heinrich, et al. Process for manufacturing (s)-3-hydroxy-1-(1h-indol-5-yl)-2-oxo-pyrrolidine-3-carboxylic acid 3,5-difluoro-benzylamide. WO2021001328A1.