CDK-IN-6，是一类吡唑并[1,5-a]嘧啶化合物，是一种具有抗癌活性的 CDK 抑制剂。
货号:ajcx33188
CAS:779353-02-5
分子式:C21H28N6O
分子量：380.49
溶解度:DMSO : 50 mg/mL (131.41 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

CDK-IN-6, a class of pyrazolo[1,5-a]pyrimidine compound, is a CDK inhibitor with anticancer activities[1].

Individual CDK’s, such as, CDK1, CDK2, CDK3, CDK4, CDK5, CDK6 and CDK7, CDK8 and the like, perform distinct roles in cell cycle progression and can be classified as either G1, S, or G2M phase enzymes. Uncontrolled proliferation is a hallmark of cancer cells, and misregulation of CDK function occurs with high frequency in many important solid tumors[1].

[1]. Timothy Guzi, et al. Novel pyrazolopyrimidines as cyclin dependent kinase inhibitors. US20040209878A1.