TCO-PEG3-NHSester是一种PROTAClinker，属于PEG类。TCO-PEG3-NHSester可用于合成一系列PROTAC分子。
货号:ajcx32498
CAS:2141981-88-4
分子式:C22H34N2O9
分子量：470.51
溶解度:DMSO: 100 mg/mL (212.54 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

TCO-PEG3-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[1]. Wang Y, et al. Degradation of proteins by PROTACs and other strategies. Acta Pharm Sin B. 2020 Feb;10(2):207-238.