An antiviral compound
货号:ajcx22038
CAS:N/A
分子式:C17H22ClF3N2O
分子量：362.8
溶解度:DMF: 11mg/mL,DMF:PBS (pH 7.2) (1:2): 0.3mg/mL,DMSO: 10mg/mL
纯度：98%
存储：Store at -20°C
库存：现货

Background:

CAY10766 is an antiviral compound.¹It inhibits entry of influenza virus-like particles pseudotyped with hemagglutinin A (HA) from H5N1 influenza A virus into A549 cells (EC₅₀= 0.24 µM). CAY10766 (1 µM) reduces H1N1 and H5N1 influenza A viral titers in infected MDCK cells. It also exhibits synergy with oseltamivir carboxylate in MDCK cells infected with the influenza A reporter PR8-NS1-Gluc virus.

1.Gaisina, I.N., Peet, N.P., Cheng, H., et al.Optimization of 4?aminopiperidines as inhibitors of influenza A viral entry that are synergistic with oseltamivirJ. Med. Chem.63(6)312-3130(2020)