Brimonidine-d4 D-tartrate

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本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

规格:	98%
分子量:	446.25

包装与价格：

包装	价格(元)
1mg	询价
5mg	询价

Brimonidine-d4 (UK 14304-d4) D-tartrate 是 Brimonidine D-tartrate 的氘代物。
货号:ajcx39408
CAS:1316758-27-6
分子式:C15H12D4BrN5O6
分子量：446.25
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Brimonidine-d4 (UK 14304-d4) D-tartrate is the deuterium labeled Brimonidine D-tartrate[1].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
[2]. Cambridge, D., UK-14,304, a potent and selective alpha2-agonist for the characterisation of alpha-adrenoceptor subtypes. Eur J Pharmacol, 1981. 72(4): p. 413-5.