Ar-V7-IN-1 是一种有效的 Ar-V7 抑制剂。AR-V7 是雄激素受体的一种激素非依赖性剪接变体。Ar-V7-IN-1具有研究各种适应症的潜力,特别是前列腺癌等癌症 (信息提取自专利 WO2018114781A1, 化合物 43)。
货号:ajcx37812
CAS:2230880-25-6
分子式:C10H10Br2N4OS
分子量:394.09
溶解度:DMSO : 83.33 mg/mL (211.45 mM; Need ultrasonic)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Ar-V7-IN-1 is a potent inhibitor of Ar-V7. AR-V7 is a hormone-independent splice variant of the androgen receptor. Ar-V7-IN-1 has the potential for the research of various indications, in particular cancers such as prostate cancer (extracted from patent WO2018114781A1, compound 43)[1].
[1]. Fuqiang Ban, et al. Ar-v7 inhibitors. Patent WO2018114781A1.