Fmoc-MMAE 是保护基团共轭连接到 MMAE。Mc-MMAE 是有效的微管蛋白抑制剂，可用于偶联抗体。
货号:ajcx35990
CAS:474645-26-6
分子式:C54H77N5O9
分子量：940.22
溶解度:DMSO : ≥ 45 mg/mL (47.86 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Fmoc-MMAE is a protective group-conjugated monomethyl auristatin E (MMAE), which is a potent tubulin inhibitor. Fmoc-MMAE can be used in the synthesis of ADC[1].

[1]. Pan D, et al. An antibody-drug conjugate targeting a GSTA glycosite-signature epitope of MUC1 expressed by non-small cell lung cancer. Cancer Med. 2020;9(24):9529-9540.