NH2-PEG7是一种PROTAClinker(PROTAClinker),属于PEG类。NH2-PEG7可用于PROTACPARP1降解剂iRucaparib-AP6的合成。
货号:ajcx31190
CAS:1425973-14-3
分子式:C14H31NO7
分子量:325.4
溶解度:DMSO: 100 mg/mL (307.31 mM); H2O:< 0.1 mg/mL (insoluble)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
NH2-PEG7 is a PROTAC linker, which refers to the PEG composition. NH2-PEG7 can be used in the synthesis of the PROTAC PARP1 degrader iRucaparib-AP6[1].
[1]. Wang S, et al. Uncoupling of PARP1 trapping and inhibition using selective PARP1 degradation. Nat Chem Biol. 2019 Dec;15(12):1223-1231.