An inactive metabolite of cyclophosphamide
货号:ajcx25272
CAS:22788-18-7
分子式:C7H15Cl2N2O4P
分子量:293.1
溶解度:Acetonitrile: soluble,DMSO: soluble,Methanol: soluble
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Carboxyphosphamide is an inactive metabolite of the alkylating agent cyclophosphamide .1It is formed from cyclophosphamideviaoxidation of the intermediate metabolite aldophosphamide by aldehyde dehydrogenase.
1.Manthey, C.L., and Sladek, N.E.Kinetic characterization of the catalysis of "activated" cyclophosphamide (4-hydroxycyclophosphamide/aldophosphamide) oxidation to carboxyphosphamide by mouse hepatic aldehyde dehydrogenasesBiochem. Pharmacol.37(14)2781-2790(1988)