An oleic acid analog
货号:ajcx25046
CAS:N/A
分子式:C19H35F3O
分子量：336.5
溶解度:Ethanol: 1 mg/ml
纯度：98%
存储：Store at -20°C
库存：
现货Background:
1(R)-(Trifluoromethyl)oleyl alcohol is an analog of oleic acid .1It inhibits ferroptosis induced by erastin in primary fibroblasts isolated from patients with Friedreich ataxia, a neuro- and cardiodegenerative disorder characterized by loss or impaired activity of frataxin (FXN), when used at concentrations of 5, 10, or 20 µM. 1(R)-(Trifluoromethyl)oleyl alcohol (5 µM) reduces lipid peroxidation induced byFXNsiRNA knockdown in NBT human myoblasts.
1.Cotticelli, M.G., Forestieri, R., Xia, S., et al.Identification of a novel oleic acid analog with protective effects in multiple cellular models of Friedreich ataxiaACS Chem. Neurosci.11(17)2535-2542(2020)
