&2#8242;-O-Methylcytidine 是一种 2'-取代的核苷,可作为 HCV 复制的抑制剂。
货号:ajcx24752
CAS:2140-72-9
分子式:C10H15N3O5
分子量:257.2
溶解度:DMSO: 0.2 mg/ml,PBS (pH 7.2): 10 mg/ml
纯度:98%
存储:Store at -20°C
库存:
现货Background:
2'-O-Methylcytidine is a nucleoside derivative and an inhibitor of hepatitis C virus (HCV) non-structural protein 5B (NS5B; IC50= 3.8 µM).1It inhibits HCV replication in a replicon assay (IC50= 21.2 µM).
1.Migliaccio, G., Tomassini, J.E., Carroll, S.S., et al.Characterization of resistance to non-obligate chain-terminating ribonucleoside analogs that inhibit hepatitis C virus replication in vitroJ. Bio. Chem.278(49)49164-49170(2003)