Dopamine D2 receptor antagonist-1 是一种多巴胺 D2 受体 (D2R) 的负变构调节剂 (NAM)，具有亚毫摩尔级别的亲和力。
货号:ajcx17028
CAS:1055411-77-2
分子式:C14H17N3S
分子量：259.37
溶解度:DMSO: 250 mg/mL (963.87 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Dopamine D2 receptor antagonist-1 is a negative allosteric modulator (NAM) of the dopamine D2 receptor (D2R) with sub-mM affinity[1].

[1]. Fyfe TJ, et al. Subtle modifications to a thieno[2,3-d]pyrimidine scaffold yield negative allosteric modulators and agonists of the dopamine D2 receptor. Eur J Med Chem. 2019 Apr 15;168:474-490.