AZD-0284是核受体RORγ的反向激动剂。在开发用于治疗寻常型斑块状银屑病和呼吸道疾病。
货号:ajcx12672
CAS:2101291-07-8
分子式:C21H18F6N2O5S
分子量：524.43
溶解度:DMSO : 100 mg/mL (190.68 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

AZD-0284 is an inverse agonist of the nuclear receptor RORγ. In development for the treatment of plaque psoriasis vulgaris and respiratory tract disorders[1].

[1]. Narjes, F, et al. The discovery of AZD0284, an inverse agonist of the nuclear receptor RORg. American Chemical Society, 2017 Drug Design and Delivery Symposium 26 October 2017