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Bergenin(Cuscutin)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Bergenin(Cuscutin)图片
CAS NO:477-90-7
规格:≥98%
包装与价格：
包装价格(元)
25mg询价
50mg询价
100mg询价
250mg询价
500mg询价
1g询价
5g询价

理化性质和储存条件
Molecular Weight (MW)328.27
FormulaC14H16O9
CAS No.477-90-7
Storage-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)DMSO: > 10 mM
Water: NA
Ethanol: NA
Other info

Chemical Name: (2R,3S,4S,4aR,10bS)-3,4,8,10-tetrahydroxy-2-(hydroxymethyl)-9-methoxy-3, 4,4a,10b-tetrahydro-2H-pyrano[3,2-c]isochromen-6-one

InChi Key: YWJXCIXBAKGUKZ-HJJNZUOJSA-N

InChi Code: InChI=1S/C14H16O9/c1-21-11-5(16)2-4-7(9(11)18)12-13(23-14(4)20)10(19)8(17)6(3-15)22-12/h2,6,8,10,12-13,15-19H,3H2,1H3/t6-,8-,10+,12+,13-/m1/s1

SMILES Code: O=C1C2=C(C(O)=C(OC)C(O)=C2)[C@@]3([H])[C@]([C@@H](O)[C@H](O)[C@@H](CO)O3)([H])O

SynonymsCuscutin
实验参考方法
In Vitro

In vitro activity: The naloxone-precipitated withdrawal symptom (jumping frequency) was significantly ameliorated (50% of control group) by administration of bergenin (20 mg/kg) in morphine-treated mice. Furthermore, morphine-induced down-regulation of glutathione (GSH) contents was reversed by bergenin administration in the frontal cortex and liver.

In VivoBergenin attenuated inflammatory cell infiltration and decreased the concentration of NO, TNF-α, IL-1β, and IL-6, which were increased in LPS-induced mouse mastitis.
Animal modelMouse
Formulation & Dosage
References

Inflammation. 2015;38(3):1142-50; Arch Pharm Res. 2015 Jun;38(6):1248-54.

 
 
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