Succinic acid-d6 (Wormwood acid-d6) 是 Succinic acid 的氘代物。Succinic acid 是三羧酸循环的中间产物，也是无氧代谢的发酵产物之一。
货号:ajcx35766
CAS:21668-90-6
分子式:C4D6O4
分子量：124.13
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Succinic acid-d6 (Wormwood acid-d6) is the deuterium labeled Succinic acid. Succinic acid is an intermediate product of the tricarboxylic acid cycle, as well as one of fermentation products of anaerobic metabolism.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Zhang YJ, et al. Optimization of succinic acid fermentation with Actinobacillus succinogenes by response surface methodology (RSM). J Zhejiang Univ Sci B. 2012 Feb;13(2):103-10.