Rebamipide mofetil是 Rebamipide (OPC12759)的口服活性前药。Rebamipide是一种粘膜保护剂。Rebamipide诱导COX-2表达,增加 PGE2 水平,并以 COX-2 依赖的方式增强胃黏膜防御。
货号:ajcx35604
CAS:1527495-76-6
分子式:C25H26ClN3O5
分子量:483.94
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Rebamipide mofetil is an orally active prodrug of Rebamipide (OPC12759). Rebamipide is a mucoprotective agent. Rebamipide induces COX-2 expression, increases PGE2 levels, and enhances gastric mucosal defense in a COX-2-dependent manner[1].
[1]. Cho, Eui Hwan, et al.Pharmaceutical composition comprising rebamipide precursor for oral administration for preventing or treating immune disease and metabolic disease.WO2017138717A1.