Nikkomycin Z,一种核苷肽,是一种选择性竞争性几丁质合成 (chitin synthesis) 抑制剂。Nikkomycin Z 具有抗真菌作用,可作为几丁质合酶底物 UDP-N-乙酰氨基葡萄糖的竞争性类似物。
货号:ajcx34260
CAS:59456-70-1
分子式:C20H25N5O10
分子量:495.44
溶解度:H2O : ≥ 100 mg/mL (201.84 mM)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Nikkomycin Z, a nucleoside-peptide, is a selective competitive chitin synthesis inhibitor. Nikkomycin Z has antifungal effects and acts as a competitive analogue of the chitin synthase substrate UDP-N-acetylglucosamine[1].
[1]. R KovÁcs, et al. Synergistic Effect of Nikkomycin Z With Caspofungin and Micafungin Against Candida Albicans and Candida Parapsilosis Biofilms. Lett Appl Microbiol. 2019 Oct;69(4):271-278.