BnO-PEG4-OH 是一种基于PEG 的 PROTAC linker,可用于 PROTAC 的合成。
货号:ajcx34248
CAS:86259-87-2
分子式:C15H24O5
分子量:284.35
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
BnO-PEG4-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
[1]. Andrew P. Crew, et al. Tau-protein targeting protacs and associated methods of use. Patent. US20180125821A1.