NH2-PEG3-C1-Boc (PROTAC Linker 5) 是一种 PROTAC linker，属于 PEG 类。NH2-PEG3-C1-Boc 可用于合成 PROTAC 分子。
货号:ajcx32578
CAS:189808-70-6
分子式:C12H25NO5
分子量：263.33
溶解度:DMSO : 100 mg/mL (379.75 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

NH2-PEG3-C1-Boc (PROTAC Linker 5) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

参考文献:
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.