A glycerolipid precursor
货号:ajcx25612
CAS:N/A
分子式:C3H6O6P·1/2Mg [XH2O]
分子量：181.2
溶解度:DMF: 1 mg/ml,PBS (pH 7.2): 1 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Dihydroxyacetone phosphate is a precursor in the biosynthesis of glycerolipids.¹It is produced by the glycolytic enzyme fructose-1,6-bisphosphate aldolase or by isomerization of glyceraldehyde-3-phosphate by triosephosphate isomerase.²Erythrocyte levels of dihydroxyacetone phosphate are increased in patients with triosephosphate isomerase deficiency, an inborn error of metabolism characterized by hemolytic anemia and progressive neurological dysfunction.³

1.Dodds, P.F., Gurr, M.I., and Brindley, D.N.The glycerol phosphate, dihydroxyacetone phosphate and monoacylglycerol pathways of glycerolipid synthesis in rat adipose-tissue homogenatesBiochem J.160(3)693-700(1976) 2.Miyazawa, H., Yamaguchi, Y., Sugiura, Y., et al.Rewiring of embryonic glucose metabolism via suppression of PFK-1 and aldolase during mouse chorioallantoic branchingDevelopment144(1)63-73(2017) 3.Orosz, F., VÉrtessy, B.G., HollÁn, S., et al.Triosephosphate isomerase deficiency: Predictions and factsJ. Theor. Biol.182(3)437-447(1996)