A neuropeptide with diverse biological activities
货号:ajcx23654
CAS:N/A
分子式:C17[13C]H17D3FN5O2
分子量：361.4
溶解度:DMSO: soluble
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Trelagliptin-¹³C-d₃is intended for use as an internal standard for the quantification of trelagliptin by GC- or LC-MS. Trelagliptin is an inhibitor of dipeptidyl peptidase 4 (DPP-4; IC₅₀= 4 nM).¹It is greater than 10,000-fold selective for DPP-4 over isopeptidases. Trelagliptin (7 mg/kg) inhibits plasma DPP-4 activity and reduces postprandial plasma insulin levels in Zuckerfa/farats. Formulations containing trelagliptin have been used in the treatment of type 2 diabetes mellitus.

1.Kushwaha, R.N., Haq, W., and Katti, S.B.Discovery of 17 gliptins in 17-years of research for the treatment of type 2 diabetes: A synthetic overviewChemistry and Biology Interface4(3)137-162(2014)