A monounsaturated fatty alcohol
货号:ajcx23180
CAS:143-28-2
分子式:C18H36O
分子量：268.5
溶解度:DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Oleyl alcohol is a monounsaturated fatty alcohol produced by the reduction of oleic acid .¹Topical application of an oleyl alcohol (5% w/w), propylene glycol, and Carbopol^®940 gel containing the non-steroidal anti-inflammatory drug (NSAID) piroxicam enhances piroxicam absorption into isolated rat abdominal skin compared to a control gel not containing oleyl alcohol.²Oleyl alcohol also increases naloxone penetration into isolated postmortem human skin when applied at a 10% concentration.³

1.Klonowski, R.S., Findley, T.W., Josefson, C.M., et al.Oleyl alcohol from animal fats by catalytic reductionJ. Am. Oil Chem. Soc.47326-328(1970) 2.Santoyo, S., Arellano, A., Ygartua, P., et al.Penetration enhancer effects on the in vitro percutaneous absorption of piroxicam through rat skinInt. J. Pharm.117(2)219-224(1995) 3.Aungst, B.J., Rogers, N.J., and Shefter, E.Enhancement of naloxone penetration through human skin in vitro using fatty acids, fatty alcohols, surfactants, sulfoxides and amidesInt. J. Pharm.33(1-3)225-234(1986)