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JWH 073 7-hydroxyindole metabolite-d7
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
JWH 073 7-hydroxyindole metabolite-d7图片
规格:98%
分子量:350.5
包装与价格:
包装价格(元)
100ug询价
500ug询价
1mg询价

A neuropeptide with diverse biological activities
货号:ajcx22726
CAS:N/A
分子式:C23H14D7NO2
分子量:350.5
溶解度:DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 20 mg/ml,Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

JWH 073 7-hydroxyindole metabolite-d7contains seven deuterium atoms at the 2, 2', 3, 3', 4, 4, and 4 positions. It is intended for use as an internal standard for the quantification of JWH 073 7-hydroxyindole metabolite by GC-or LC-mass spectrometry (MS). JWH 073 is a mildly selective agonist of the central cannabinoid (CB1) receptor derived from the aminoalkylindole WIN 55,212-2. The Kivalues for binding CB1and the peripheral cannabinoid (CB2) receptor are 8.9 and 38 nM, respectively for a CB1:CB2ratio of 0.23.1JWH 073 is one of several synthetic CBs which have been included in smoking mixtures. JWH 073 7-hydroxyindole metabolite is expected to be a urinary metabolite of JWH 073 based on the metabolism of the closely-related JWH 015 and JWH 018.2,3


1.Aung, M.M., Griffin, G., Huffman, J.W., et al.Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor bindingDrug Alcohol Depend.60(2)133-140(2000) 2.Zhang, Q., Ma, P., Cole, R.B., et al.Identification of in vitro metabolites of JWH-015, an aminoalkylindole agonist for the peripheral cannabinoid receptor (CB2) by HPLC-MS/MSAnalytical and Bioanalytical Chemistry3861345-1355(2006) 3.Sobolevsky, T., Prasolov, I., and Rodchenkov, G.Detection of JWH-018 metabolites in smoking mixture post-administration urineForensic Sci. Int.200(1-3)141-147(2010)

 
 
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