A halogenated form of lauric acid
货号:ajcx21078
CAS:73367-80-3
分子式:C12H23BrO2
分子量：279.2
溶解度:DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

12-Bromododecanoic acid is a halogenated form of lauric acid . It has been used in the synthesis of clickable forms of myristic acid and as a model fatty acid ligand to determine the X-ray crystal structure of bovine β-lactoglobulin-ligand complexes.^1,212-Bromododecanoic acid (10 µg/ml) reduces virion DNA in the culture supernatant of primary hepatocytes isolated from a duckling model of hepatitis B virus (HBV) infection and inhibits HIV replication in CEM-SS T cells (EC₅₀= 38 µM).³

1.Heal, W.P., Wickramasinghe, S.R., Leatherbarrow, R.J., et al.N-Myristoyl transferase-mediated protein labelling in vivoOrg. Biomol. Chem.6(13)2308-2315(2008) 2.Qin, B.Y., Creamer, L.K., Baker, E.N., et al.12-Bromododecanoic acid binds inside the calyx of bovine β-lactoglobulinFEBS Lett.438(3)272-278(1998) 3.Parang, K., Wiebe, L.I., Knaus, E.E., et al.In vitro antiviral activities of myristic acid analogs against human immunodeficiency and hepatitis B virusesAntiviral Res.34(3)75-90(1997)