Lanopepden(GSK1322322)是一种肽去甲酰酶抑制剂,可抑制金黄色葡萄球菌。抑制ATCC29213和ATCC25923菌株,MIC都为1mg/L。
货号:ajcx12784
CAS:1152107-25-9
分子式:C22H34FN7O4
分子量:479.55
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Lanopepden (GSK 1322322) is a peptide deformylase inhibitor active against Staphylococcus aureus strains with MICs of 1 and 1 mg/L for ATCC 29213 and ATCC 25923 strain, respectively[1].
[1]. Peyrusson F, et al. Cellular pharmacokinetics and intracellular activity of the novel peptide deformylase inhibitor GSK1322322 against Staphylococcus aureus laboratory and clinical strains with various resistance phenotypes: studies with human THP-1 monocytes and J774 murine macrophages. Antimicrob Agents Chemother. 2015 Sep;59(9):5747-60.