SENP1-IN-1 是特异性去 SUMO 化蛋白酶 SENP1 的抑制剂,详细请参考专利文献 CN110627860,化合物 29。SENP1-IN-1 被开发用于增强肿瘤放射敏感性。
货号:ajcx39640
CAS:2416910-69-3
分子式:C35H58N2O4
分子量:570.85
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
SENP1-IN-1 is a specific deSUMOylation protease 1 (SENP1) inhibitor extracted from patent CN110627860, Compound 29. SENP1-IN-1 is developed for tumor radiosensitivity enhancement[1].
SENP1-IN-1 may improve the sensitivity of tumor cells to irradiation[1].SENP1-IN-1 (0.7-20 μM; 72 hours)has cytotoxic for Hella cells with an IC50 of >20μM[1].
[1]. Li, Yiliang, et al. Preparation of ursolic acid derivatives useful as SENP1 inhibitors and tumor radiosensitizer. CN110627860A.