FT895 是一种有效的选择性 HDAC11 抑制剂,IC50 为 3 nM。
货号:ajcx39126
CAS:2225728-57-2
分子式:C16H15F3N4O2
分子量:352.31
溶解度:DMSO : 125 mg/mL (354.80 mM; Need ultrasonic)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
FT895 is a potent and selective HDAC11 inhibitor with an IC50 of 3 nM[1].
FT895 is a highly selective HDAC11 inhibitor showing greater than 1000-fold selectivity against the other 10 members of the HDAC family[1].
[1]. Martin MW, et al. Discovery of novel N-hydroxy-2-arylisoindoline-4-carboxamides as potent and selective inhibitors of HDAC11. Bioorg Med Chem Lett. 2018 Jul 1;28(12):2143-2147.
Protocol: