与PROTACs诱导三元复合物的能力类似,PhosTAC7专注于将Ser/Thr磷酸酶招募到磷酸化底物以介导其去磷酸化。
货号:ajcx37432
CAS:N/A
分子式:C58H87ClN2O17
分子量:1119.77
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Similar to PROTACs in their ability to induce ternary complexes, PhosTAC7 focuses on recruiting a Ser/Thr phosphatase to a phosphosubstrate to mediate its dephosphorylation.
[1]. Chen PH, et al. Modulation of Phosphoprotein Activity by Phosphorylation Targeting Chimeras (PhosTACs). ACS Chem. Biol. 2021 Nov 15.