Mal-PEG10-NHS ester 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。
货号:ajcx36312
CAS:N/A
分子式:C31H50N2O16
分子量：706.73
溶解度:DMSO : 100 mg/mL (141.50 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Mal-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-991.