Cevidoplenib 是一种具有口服活性的脾脏酪氨酸激酶 (Syk) 抑制剂，具有潜在的抗炎和免疫调节作用。
货号:ajcx35662
CAS:1703788-21-9
分子式:C25H27N7O3
分子量：473.53
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Cevidoplenib is an orally available inhibitor of spleen tyrosine kinase (Syk), with potential anti-inflammatory and immunomodulating activities[1][2].

Upon oral administration, cevidoplenib binds to and inhibits the activity of SYK, blocking Fc receptor and B-cell receptor (BCR)-mediated signaling in inflammatory cells, including macrophages, neutrophils, mast cells, natural killer (NK) cells and B cells[2].

[1]. International Nonproprietary Names for Pharmaceutical Substances (INN). WHO Drug Information, Vol. 31, No. 4, 2017.
[2]. cevidoplenib dimesylate.