Damascenone ((E/Z)-Damascenone) 源于 Epipremnum pinnatum 的具有抗炎活性的活性化合物。Damascenone 是E- 和Z- 异构体大马士革酮的混合物。
货号:ajcx34192
CAS:23696-85-7
分子式:C13H18O
分子量：190.28
溶解度:DMSO : 100 mg/mL (525.54 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Damascenone ((E/Z)-Damascenone) is an active compound of Epipremnum pinnatum with anti-inflammatory activity[1]. Damascenone is a mixture complex of E-isomer-Damascenone and Z-isomer Damascenone.

β-Damascenone also inhibits the upregulation of inflammatory proteins as demonstrated by immune assays for cell surface E-selectin and secreted TNF-α[1].β-Damascenone inhibits NF-κB signaling pathway in vitro in human cellular systems that has been activated with different inflammatory stimuli[1].

[1]. San-Po Pan, et al. C13 Megastigmane Derivatives From Epipremnum pinnatum: β-Damascenone Inhibits the Expression of Pro-Inflammatory Cytokines and Leukocyte Adhesion Molecules as Well as NF-κB Signaling