HS-PEG3-CH2CH2NH2hydrochloride(Thiol-PEG3-aminehydrochloride)是一种PROTAClinker，属于PEG类。可用于合成PROTAC分子。
货号:ajcx32088
CAS:N/A
分子式:C8H20ClNO3S
分子量：245.77
溶解度:DMSO: 250 mg/mL (1017.21 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

HS-PEG3-CH2CH2NH2 hydrochloride (Thiol-PEG3-amine hydrochloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562