S961acetate是一种高亲和力的胰岛素受体(insulinreceptor,IR)拮抗剂，对HIR-A，HIR-B和人胰岛素样生长因子I受体(HIGF-IR)的IC50分别为0.048，0.027和630nM。
货号:ajcx31988
CAS:N/A
分子式:C213H301N55O72S2
分子量：4864.18
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

S961 acetate is an high-affinity and selective insulin receptor (IR) antagonist with IC50s of 0.048, 0.027, and 630 nM for HIR-A, HIR-B, and human insulin-like growth factor I receptor (HIGF-IR) in SPA-assay, respectively[1].

S961 also shows high-affinity to Rat IR and Pig IR with IC50s of 0.056 nM and 0.084 nM in PEG-assay, respectively[1].

[1]. SchÄffer L, et al. A novel high-affinity peptide antagonist to the insulin receptor. Biochem Biophys Res Commun. 2008 Nov 14;376(2):380-3.