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N-(Azido-PEG3)-N-Fluorescein-PEG4-acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
N-(Azido-PEG3)-N-Fluorescein-PEG4-acid图片
规格:98%
分子量:855.91
包装与价格:
包装价格(元)
1mg询价
5mg询价

N-(Azido-PEG3)-N-Fluorescein-PEG4-acid是一种PROTAClinker,属于PEG类。可用于合成PROTAC分子。
货号:ajcx31138
CAS:2100306-72-5
分子式:C40H49N5O14S
分子量:855.91
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:现货

Background:

N-(Azido-PEG3)-N-Fluorescein-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].


[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 
 
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