Davunetide 是一种八氨基酸片段,来源于活动依赖性神经保护蛋白 (ADNP),ADNP 是哺乳动物 CNS 中存在的一种神经营养因子。
货号:ajcx28140
CAS:211439-12-2
分子式:C36H60N10O12
分子量:824.93
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Highly potent active component of activity-dependent neuroprotective protein (ADNP). Prevents β-amyloid aggregation. Reduces hyperphosphorylated tau levels and increases tau-microtubule interactions; neuroprotective at femtomolar concentrations in vitro. Exerts neuroprotective effects in schizophrenia models associated with microtubule-autophagy insufficiency in MAP6-deficient mice. Modulates HIFs and VEGF expression and suppresses retinal cell apoptosis in an in vivo diabetic retinopathy model.