5(6)-Carboxy-2&prime,7&prime-dichlorofluorescein diacetate

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规格:	98%
分子量:	529.3

包装与价格：

包装	价格(元)
25mg	询价
50mg	询价
100mg	询价

5(6)-Carboxy-&2#8242;,7′-dichlorofluorescein diacetate 是一种细胞透过性荧光指示剂。
货号:ajcx25638
CAS:127770-45-0
分子式:C25H14Cl2O9
分子量：529.3
溶解度:DMF: 30 mg/ml,DMSO: 30 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

5(6)-Carboxy-2’,7’-dichlorofluorescein diacetate is an oxidant-sensitive and cell-permeable fluorescent probe.¹Base hydrolysis of the ester bonds by intracellular esterases releases the acetate groups and the resulting compound, 5(6)-carboxy-2’,7’,-dichlorofluorescein, is oxidized by reactive oxygen species (ROS) and nitric oxide (NO) and displays excitation/emission maxima of 504 and 530 nm, respectively, which can be quantified as a measure of oxidant production.

1.Hempel, S.L., Buettner, G.R., O’Malley, Y.Q., et al.Dihydrofluorescein diacetate is superior for detecting intracellular oxidants: Comparison with 2’,7’-dichlorodihydrofluorescein diacetate, 5(and 6)-carboxy-2’,7’-dichlorodihydrofluorescein diacetate, and dihydrorhodamine 123Free Radic. Biol. Med.27(1-2)146-159(1999)