A neuropeptide with diverse biological activities
货号:ajcx22734
CAS:N/A
分子式:C25H20D5NO3
分子量:392.5
溶解度:DMF: 15 mg/ml,DMF:PBS (pH 7.2) (1:5): 0.1 mg/ml,DMSO: 10 mg/ml,Ethanol: 10 mg/ml
纯度:98%
存储:Store at -20°C
库存:
现货Background:
JWH 081 N-(5-hydroxypentyl) metabolite-d5contains five deuterium atoms at the 2, 4, 5, 6, and 7 positions. It is intended for use as an internal standard for the quantification of JWH 081 N-(5-hydroxypentyl) metabolite by GC-or LC-mass spectrometry. Cannabimimetic indoles, including certain "JWH" compounds, have been identified in herbal blends.1Hydroxylated and glucuronidated metabolites of two closely-related compounds, JWH 015 and JWH 018 , have been identified fromin vitroliver microsomal metabolism and from urine, respectively.2,3,4JWH 081 is a cannabimimetic indole that is structurally-and functionally-related to JWH 015 and JWH 018. JWH 081 N-(5-hydroxypentyl) metabolite is expected to be a metabolite of JWH 081 that would be detectable both in serum and in urine.
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2.Zhang, Q., Ma, P., Cole, R.B., et al.Identification of in vitro metabolites of JWH-015, an aminoalkylindole agonist for the peripheral cannabinoid receptor (CB2) by HPLC-MS/MSAnalytical and Bioanalytical Chemistry3861345-1355(2006)
3.Sobolevsky, T., Prasolov, I., and Rodchenkov, G.Detection of JWH-018 metabolites in smoking mixture post-administration urineForensic Sci. Int.200(1-3)141-147(2010)
4.Moran, C.L., Le, V.H., Chimalakonda, K.C., et al.Quantitative measurement of JWH-018 and JWH-073 metabolites excreted in human urineAnal. Chem.83(11)4228-4236(2011)