AR-13324类似物甲磺酸盐是AR-13324的类似物。
货号:ajcx13336
CAS:N/A
分子式:C29H33N3O9S2
分子量:631.72
溶解度:DMSO : ≥ 28 mg/mL (44.32 mM)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
AR-13324 analog mesylate is a small-molecule inhibitor of Rho kinase and a norepinephrine transporter; reduces intraocular pressure (IOP) in normotensive monkey eyes.
[1]. Wang RF, et al. Effect of 0.04% AR-13324, a ROCK, and norepinephrine transporter inhibitor, on aqueous humor dynamics in normotensive monkey eyes. J Glaucoma. 2015 Jan;24(1):51-4. [2]. Levy B, et al. Ocular hypotensive safety and systemic absorption of AR-13324 ophthalmic solution in normal volunteers. Am J Ophthalmol. 2015 May;159(5):980-5.e1.