Indotecan(LMP-400)

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Indotecan(LMP-400)

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

规格:	98%
分子量:	478.49

Indotecan(LMP-400)是一种有效的topoisomerase1(Top1)抑制剂。Indotecan(LMP-400)对P388,HCT116,MCF-7细胞系的IC50值分别为300,1200,560nM。
货号:ajcx12906
CAS:915303-09-2
分子式:C26H26N2O7
分子量：478.49
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Indotecan (LMP-400) is a potent topoisomerase 1(Top1) inhibitor with IC50 values of 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively.

[1]. Seol Y, et al. Single-Molecule Supercoil Relaxation Assay as a Screening Tool to Determine the Mechanism and Efficacy of Human Topoisomerase IB Inhibitors. Mol Cancer Ther. 2015 Nov;14(11):2552-9.