Fuorescent oligoDNA probe
货号:ajcx11294
CAS:
分子式:C57H55N4O8P
分子量：955.04
溶解度:good in dichloromethane and acetonitrile
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Pyrene is polycyclic aromatic hydrocarbon which is well-known for its ability to intercalate into DNA. Pyrene features intense blue fluorescence. Its parameters depend strongly on fluorophore microenvironment. Therefore, fluorescence spectra of pyrene are used for the extraction of structural information about site surrounding pyrene. Two pyrenes in close proximity usually form excimers easily detectable by excimer fluorescence. Pyrene can also be a FRET donor to other fluorophores such as perylene. With this phosphoramidite, pyrene can be introduced into DNA or RNA by means of automated synthesis. This pyrene phosphoramidite contains hydrocarbon moiety rigidly attached to deoxyuridine. This reagent allows to attach pyrene fragment to 5', internal, or 3' position (using universal support). This amidite requires no special handling, coupling, or deprotection conditions. Recommended diluent for it is acetonitrile. Pyrene dU amidite